The Essential Role of Vitamin B6 & B12: Health Benefits and Impact of Alcohol

Vitamin B6 (pyridoxine) & Vitamin B12 (cyanocobalamin)

Vitamin B6 and B12 play a major role in keeping the nervous system and immune system healthy. Vitamin B helps with cognitive development through biosynthesis of neurotransmitters and maintaining normal levels of homocysteine in the blood; high levels of homocysteine have been proven to be very dangerous.

As for healthy immune function, Vitamin B is involved in gluconeogenesis and glycogenolysis which promotes interleukin-2, lymphocyte, and hemoglobin formation. Additionally, Vitamin B helps energy levels and plays a role in digestion by allowing for protein, lipid, and carbohydrate metabolism. Many people are deficient in Vitamin B and take supplements to increase their levels. 


A randomized controlled crossover study was conducted to see how alcohol affects the levels of Vitamin B in a group of 78 study participants. Participants who consumed alcohol were found to have increased homocysteine levels and lower levels of Vitamin B in their blood; it is believed that this result is due to alcohol affecting the absorption, storage, and metabolism of vitamins.

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